Most relevant publications of our group from the last three years:

Götz, M. P., Skjoedt, M.-O., Bayarri-Olmos, R., Hansen, C. B., Pérez-Alós, L., Jarlhelt, I., Benfield, T., Rosbjerg, A., & Garred, P. (2022). Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19. Journal of Innate Immunity, 1–14. https://doi.org/10.1159/000525508

Pérez-Alós, L., Armenteros, J. J. A., Madsen, J. R., Hansen, C. B., Jarlhelt, I., Hamm, S. R., Heftdal, L. D., Pries-Heje, M. M., Møller, D. L., Fogh, K., Hasselbalch, R. B., Rosbjerg, A., Brunak, S., Sørensen, E., Larsen, M. A. H., Ostrowski, S. R., Frikke-Schmidt, R., Bayarri-Olmos, R., Hilsted, L. M., … Garred, P. (2022). Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors. Nature Communications, 13(1), 1614. https://doi.org/10.1038/s41467-022-29225-4

Hansen, C. B., Sandholdt, H., Møller, M. E. E., Pérez-Alós, L., Pedersen, L., Bastrup Israelsen, S., Garred, P., & Benfield, T. (2022). Prediction of Respiratory Failure and Mortality in COVID-19 Patients Using Long  Pentraxin PTX3. Journal of Innate Immunity, 14(5), 493–501. https://doi.org/10.1159/000521612

Bayarri-Olmos, R., Johnsen, L. B., Idorn, M., Reinert, L. S., Rosbjerg, A., Vang, S., Hansen, C. B., Helgstrand, C., Bjelke, J. R., Bak-Thomsen, T., Paludan, S. R., Garred, P., & Skjoedt, M.-O. (2021). The alpha/B.1.1.7 SARS-CoV-2 variant exhibits significantly higher affinity for  ACE-2 and requires lower inoculation doses to cause disease in K18-hACE2 mice. ELife, 10. https://doi.org/10.7554/eLife.70002

Jarlhelt, I., Nielsen, S. K., Jahn, C. X. H., Hansen, C. B., Pérez-Alós, L., Rosbjerg, A., Bayarri-Olmos, R., Skjoedt, M.-O., & Garred, P. (2021). SARS-CoV-2 Antibodies Mediate Complement and Cellular Driven Inflammation. Frontiers in Immunology, 12, 767981. https://doi.org/10.3389/fimmu.2021.767981

Bayarri-Olmos, R., Jarlhelt, I., Johnsen, L. B., Hansen, C. B., Helgstrand, C., Rose Bjelke, J., Matthiesen, F., Nielsen, S. D., Iversen, K. K., Ostrowski, S. R., Bundgaard, H., Frikke-Schmidt, R., Garred, P., & Skjoedt, M.-O. (2021). Functional Effects of Receptor-Binding Domain Mutations of SARS-CoV-2 B.1.351 and  P.1 Variants. Frontiers in Immunology, 12, 757197. https://doi.org/10.3389/fimmu.2021.757197

Bayarri-Olmos, R., Idorn, M., Rosbjerg, A., Pérez-Alós, L., Hansen, C. B., Johnsen, L. B., Helgstrand, C., Zosel, F., Bjelke, J. R., Öberg, F. K., Søgaard, M., Paludan, S. R., Bak-Thomsen, T., Jardine, J. G., Skjoedt, M.-O., & Garred, P. (2021). SARS-CoV-2 Neutralizing Antibody Responses towards Full-Length Spike Protein and  the Receptor-Binding Domain. Journal of Immunology (Baltimore, Md. : 1950), 207(3), 878–887. https://doi.org/10.4049/jimmunol.2100272

Hansen, C. B., Jarlhelt, I., Hasselbalch, R. B., Hamm, S. R., Fogh, K., Pries-Heje, M. M., Møller, D. L., Heftdal, L. D., Pérez-Alós, L., Sørensen, E., Larsen, M. A. H., Skjoedt, M.-O., Ostrowski, S. R., Frikke-Schmidt, R., Bayarri-Olmos, R., Hilsted, L. M., Bundgaard, H., Nielsen, S. D., Iversen, K. K., & Garred, P. (2021). Antibody-dependent neutralizing capacity of the SARS-CoV-2 vaccine BNT162b2 with  and without previous COVID-19 priming. In Journal of internal medicine (Vol. 290, Issue 6, pp. 1272–1274). https://doi.org/10.1111/joim.13366

Rosbjerg, A., Würzner, R., Garred, P., & Skjoedt, M.-O. (2021). MASP-1 and MASP-3 Bind Directly to Aspergillus fumigatus and Promote Complement  Activation and Phagocytosis. Journal of Innate Immunity, 13(4), 211–224. https://doi.org/10.1159/000514546

Jarlhelt, I., Pilely, K., Clausen, J. B., Skjoedt, M.-O., Bayarri-Olmos, R., & Garred, P. (2020). Circulating Ficolin-2 and Ficolin-3 Form Heterocomplexes. Journal of Immunology (Baltimore, Md. : 1950), 204(7), 1919–1928. https://doi.org/10.4049/jimmunol.1900694

Kirketerp-Møller, N., Bayarri-Olmos, R., Krogfelt, K. A., & Garred, P. (2020). C1q/TNF-Related Protein 6 Is a Pattern Recognition Molecule That Recruits  Collectin-11 from the Complement System to Ligands. Journal of Immunology (Baltimore, Md. : 1950), 204(6), 1598–1606. https://doi.org/10.4049/jimmunol.1901316